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Generalised Anxiety Disorder Scale (GAD-7)

The Generalized Anxiety Disorder Scale is a self-report questionnaire commonly used to assess the severity of anxiety symptoms in individuals. The 7-question scale is known by its acronym GAD-7. It was designed by Dr Robert Spitzer and colleagues at Columbia University in 2006. The GAD-7 consists of seven questions that measure the frequency and intensity of anxiety-related experiences over the past two weeks. It is widely used in health research due to its simplicity, brevity, and ability to screen and monitor anxiety symptoms reliably. It helps healthcare professionals and researchers identify individuals at risk of anxiety disorders, track symptom severity, evaluate treatment effectiveness, and make informed decisions regarding interventions and support. The GAD-7 has demonstrated good validity and reliability, making it a valuable tool for assessing anxiety in a range of settings.1Spitzer RL, Kroenke K, Williams JB, Löwe B. A brief measure for assessing generalized anxiety disorder: the GAD-7. Arch Intern Med. 2006 May 22;166(10):1092-7. doi: 10.1001/archinte.166.10.1092.2Löwe B, Decker O, Müller S, Brähler E, Schellberg D, Herzog W, Herzberg PY. Validation and standardization of the Generalized Anxiety Disorder Screener (GAD-7) in the general population. Med Care. 2008 Mar;46(3):266-74. doi: 10.1097/MLR.0b013e318160d093.3Doi S, Ito M, Takebayashi Y, Muramatsu K, Horikoshi M. Factorial Validity and Invariance of the 7-Item Generalized Anxiety Disorder Scale (GAD-7) Among Populations With and Without Self-Reported Psychiatric Diagnostic Status. Front Psychol. 2018 Sep 19;9:1741. doi: 10.3389/fpsyg.2018.01741.

In plain English, the GAD-7 is like a brief health check-up for your mind, focusing specifically on signs of anxiety. After answering the seven questions, your answers are tallied to give a score. This score can help medical professionals, such as psychologists or general practitioners, understand how severe your anxiety might be and whether further evaluation or treatment is needed. However, it’s important to remember that while the GAD-7 is a useful screening tool, it’s not a substitute for a full medical diagnosis.4Johnson SU, Ulvenes PG, Øktedalen T, Hoffart A. Psychometric Properties of the General Anxiety Disorder 7-Item (GAD-7) Scale in a Heterogeneous Psychiatric Sample. Front Psychol. 2019 Aug 6;10:1713. doi: 10.3389/fpsyg.2019.01713.

Sometimes, there is an 8th question in the GAD-7 that is not a part of the main scoring but serves as a supplementary question to gauge the impact of anxiety on your daily life. It usually asks how difficult these anxiety symptoms have made it for you to do your work, take care of things at home, or get along with other people. This additional question helps clinicians and researchers understand the extent to which anxiety is affecting your day-to-day functioning.

Why is the GAD-7 used in the Chuckling Goat Gut Microbiome Test?

There is growing evidence of a bidirectional relationship between anxiety and gut microbes. This relationship highlights the importance of the gut-brain connection or gut-brain axis. Research suggests that alterations in the gut microbiota composition, known as dysbiosis, may contribute to developing or exacerbating anxiety symptoms.5Bisgaard TH, Allin KH, Elmahdi R, Jess T. The bidirectional risk of inflammatory bowel disease and anxiety or depression: A systematic review and meta-analysis. Gen Hosp Psychiatry. 2023 Jul-Aug;83:109-116. doi: 10.1016/j.genhosppsych.2023.05.002.6Kumar A, Pramanik J, Goyal N, Chauhan D, Sivamaruthi BS, Prajapati BG, Chaiyasut C. Gut Microbiota in Anxiety and Depression: Unveiling the Relationships and Management Options. Pharmaceuticals (Basel). 2023 Apr 9;16(4):565. doi: 10.3390/ph16040565.7Butler MI, Bastiaanssen TFS, Long-Smith C, Morkl S, Berding K, Ritz NL, Strain C, Patangia D, Patel S, Stanton C, O’Mahony SM, Cryan JF, Clarke G, Dinan TG. The gut microbiome in social anxiety disorder: evidence of altered composition and function. Transl Psychiatry. 2023 Mar 20;13(1):95. doi: 10.1038/s41398-023-02325-5. This is believed to occur through various mechanisms, including the production of neurotransmitters and metabolites, regulation of the immune system, and communication between the gut and brain via the vagus nerve. Conversely, anxiety and stress can also impact the gut microbiota composition and function.8Toribio-Mateas M. Harnessing the Power of Microbiome Assessment Tools as Part of Neuroprotective Nutrition and Lifestyle Medicine Interventions. Microorganisms. 2018 Apr 25;6(2):35. doi: 10.3390/microorganisms6020035.9Anand N, Gorantla VR, Chidambaram SB. The Role of Gut Dysbiosis in the Pathophysiology of Neuropsychiatric Disorders. Cells. 2022 Dec 23;12(1):54. doi: 10.3390/cells12010054.

Using the GAD-7 in a friendly format as part of the Chuckling Goat Gut Microbiome Test helps you understand the interplay between your gut microbes and anxiety. Conversely, Chuckling Goat scientists will use this knowledge to further the research into therapeutic approaches targeting the gut microbiome and mental health.

Where to find your anxiety score in the Chuckling Goat Gut Microbiome Test

You will find your anxiety score based on the GAD-7 scale in the “Mental Wellness” report in your Chuckling Goat Gut Microbiome Test results. It’s important to highlight that your anxiety score is not diagnostic. It is provided for educational purposes and translated into a user-friendly 0-to-10 scale to help you understand the relationship between anxiety and your gut microbiome.

If you need help for a mental health crisis or emergency, you should get immediate expert advice and assessment. Visit the NHS website to find out where to get urgent help for mental health.

Synonyms: Generalised Anxiety Disorder Scale, GAD-7, validated anxiety questionnaire, general anxiety disorder questionnaire, self-reported anxiety questionnaire, anxiety questionnaire for health research, anxiety questionnaire for gut-brain connection research

Important disclaimer

The Chuckling Goat Gut Microbiome Handbook is an educational resource built to translate complex science into plain English. The information provided on this page is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your GP or other qualified health provider with any questions you may have regarding a medical condition. Always check with your GP for interactions with medications/health conditions before changing your diet or starting to take food supplements.

References

  • 1
    Spitzer RL, Kroenke K, Williams JB, Löwe B. A brief measure for assessing generalized anxiety disorder: the GAD-7. Arch Intern Med. 2006 May 22;166(10):1092-7. doi: 10.1001/archinte.166.10.1092.
  • 2
    Löwe B, Decker O, Müller S, Brähler E, Schellberg D, Herzog W, Herzberg PY. Validation and standardization of the Generalized Anxiety Disorder Screener (GAD-7) in the general population. Med Care. 2008 Mar;46(3):266-74. doi: 10.1097/MLR.0b013e318160d093.
  • 3
    Doi S, Ito M, Takebayashi Y, Muramatsu K, Horikoshi M. Factorial Validity and Invariance of the 7-Item Generalized Anxiety Disorder Scale (GAD-7) Among Populations With and Without Self-Reported Psychiatric Diagnostic Status. Front Psychol. 2018 Sep 19;9:1741. doi: 10.3389/fpsyg.2018.01741.
  • 4
    Johnson SU, Ulvenes PG, Øktedalen T, Hoffart A. Psychometric Properties of the General Anxiety Disorder 7-Item (GAD-7) Scale in a Heterogeneous Psychiatric Sample. Front Psychol. 2019 Aug 6;10:1713. doi: 10.3389/fpsyg.2019.01713.
  • 5
    Bisgaard TH, Allin KH, Elmahdi R, Jess T. The bidirectional risk of inflammatory bowel disease and anxiety or depression: A systematic review and meta-analysis. Gen Hosp Psychiatry. 2023 Jul-Aug;83:109-116. doi: 10.1016/j.genhosppsych.2023.05.002.
  • 6
    Kumar A, Pramanik J, Goyal N, Chauhan D, Sivamaruthi BS, Prajapati BG, Chaiyasut C. Gut Microbiota in Anxiety and Depression: Unveiling the Relationships and Management Options. Pharmaceuticals (Basel). 2023 Apr 9;16(4):565. doi: 10.3390/ph16040565.
  • 7
    Butler MI, Bastiaanssen TFS, Long-Smith C, Morkl S, Berding K, Ritz NL, Strain C, Patangia D, Patel S, Stanton C, O’Mahony SM, Cryan JF, Clarke G, Dinan TG. The gut microbiome in social anxiety disorder: evidence of altered composition and function. Transl Psychiatry. 2023 Mar 20;13(1):95. doi: 10.1038/s41398-023-02325-5.
  • 8
    Toribio-Mateas M. Harnessing the Power of Microbiome Assessment Tools as Part of Neuroprotective Nutrition and Lifestyle Medicine Interventions. Microorganisms. 2018 Apr 25;6(2):35. doi: 10.3390/microorganisms6020035.
  • 9
    Anand N, Gorantla VR, Chidambaram SB. The Role of Gut Dysbiosis in the Pathophysiology of Neuropsychiatric Disorders. Cells. 2022 Dec 23;12(1):54. doi: 10.3390/cells12010054.

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