Live Chat 8am - 8pm
FREE Next Day Delivery on orders over £25
FREE lifetime support


Acetate is produced in the gut through the fermentation of complex carbohydrates by several key bacterial groups. Bacteria such as Bacteroides, Prevotella, and Ruminococcus are involved in the breakdown of dietary fibres, generating acetate as a byproduct of their metabolism.

Here are five key roles of acetate in human health:

  1. Gut Health: Acetate helps maintain a healthy gut environment by supporting the integrity of the gut lining and enhancing barrier function.
  2. Energy Source: Acetate provides a valuable energy source for various cells in the body, including those in the brain, skeletal muscle, adipose tissue (fat cells), and liver cells.
  3. Metabolic Regulation: Acetate contributes to the regulation of glucose and lipid (fat) metabolism, influencing processes like how sensitive cells are to insulin and how much fat is stored around organs. Additionally, acetate plays a role in appetite control.
  4. Anti-inflammatory Effects: Acetate has anti-inflammatory properties. This means acetate helps reduce inflammation in the body and contribute to overall wellbeing.
  5. Neurotransmitter Regulation: Acetate can influence the production of neurotransmitters such as acetylcholine, gamma-aminobutyric acid (GABA), and glutamate. These neurotransmitters play important roles in cognitive function, mood regulation, and overall brain health. Acetate’s impact on neurotransmitter regulation contributes to its potential influence on mood and cognitive function.

In summary, acetate plays important roles in gut health, as a crucial energy source, reducing inflammation, supporting the metabolic and neurotransmitter regulation. As a result, acetate contributes to overall physical and mental wellbeing.

A fun fact about acetate

There is acetate in vinegar, 4% to 8% to be precise, depending on the vinegar type. This contributes to its distinctive taste and aroma. In fact, acetic acid, the main component of vinegar, is formed through the oxidation of ethanol by acetic acid bacteria. The acetic acid then dissociates into acetate ions and hydrogen ions, resulting in the sour taste and characteristic smell associated with vinegar.

Where to find your acetate score in the Chuckling Goat Gut Microbiome Test

The Chuckling Goat Gut Microbiome Test features your acetate score in the postbiotics report. Guidance on how to work with your acetate score will be featured in your personal action plan. Please note that this information is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your GP or other qualified health provider if you have any questions about the impact of acetate on your health.

Important disclaimer

The Chuckling Goat Gut Microbiome Handbook is an educational resource built to translate complex science into plain English. The information provided on this page is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your GP or other qualified health provider with any questions you may have regarding a medical condition. Always check with your GP for interactions with medications/health conditions before changing your diet or starting to take food supplements.

Questions? Talk to a Nutritional Therapist on live chat!

More from The Gut Health Express