Pseudomonas

Pseudomonas is a genus of bacteria that contains various species, some of which can significantly impact human health and cause disease. Here is an overview of how Pseudomonas interacts with human health:

Opportunistic and nosocomial infections: Pseudomonas aeruginosa is the most common species associated with human infections. It can cause opportunistic infections, particularly in immunocompromised individuals or those with underlying health conditions. Infections can involve the respiratory tract, urinary tract, skin, and soft tissues. P. aeruginosa is known for causing hospital-acquired infections, often linked to contaminated medical devices, catheters, or surgical wounds. Strict infection control measures in healthcare settings are essential to prevent its spread.¹²³
Antibiotic resistance: Pseudomonas species, especially P. aeruginosa, can develop antibiotic resistance, complicating infection treatment. Some strains exhibit multidrug resistance, necessitating the use of alternative treatments or combination therapy using different antimicrobials.⁴⁵
Biofilm formation: Pseudomonas species can form biofilms, contributing to antibiotic resistance and persistence in various environments. This characteristic makes it challenging to eradicate bacteria from surfaces and medical devices.⁶⁷
Cystic fibrosis complications: P. aeruginosa is a common pathogen affecting people with cystic fibrosis. It can lead to chronic lung infections and reduced lung function over time.⁸⁹

In summary, Pseudomonas bacteria, particularly P. aeruginosa, play a significant role in human health, causing opportunistic, nosocomial, and chronic infections. Understanding and addressing the risks associated with Pseudomonas species is crucial for protecting the delicate balance of the gut microbial ecosystem.

Where to find Pseudomonas in the Chuckling Goat Gut Microbiome Test

You will find your Pseudomonas scores in the “Pathogens” report in your Chuckling Goat Gut Microbiome Test results. Guidance on how to work with pathogens like Pseudomonas will be featured in your Personal Action Plan. Please note that this information is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your GP or other qualified health provider if you have any questions about Pseudomonas.

Synonyms: Pseudomonas aeruginosa, P. aeruginosa, Pseudomonas species

Important disclaimer

The Chuckling Goat Gut Microbiome Handbook is an educational resource built to translate complex science into plain English. The information provided on this page is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your GP or other qualified health provider with any questions you may have regarding a medical condition. Always check with your GP for interactions with medications/health conditions before changing your diet or starting to take food supplements.

References

1
de Bentzmann S, Plésiat P. The Pseudomonas aeruginosa opportunistic pathogen and human infections. Environ Microbiol. 2011 Jul;13(7):1655-65. doi: 10.1111/j.1462-2920.2011.02469.x.
2
Iglewski BH. Pseudomonas. In: Baron S, editor. Medical Microbiology. 4th edition. Galveston (TX): University of Texas Medical Branch at Galveston; 1996. Chapter 27. Available from: https://www.ncbi.nlm.nih.gov/books/NBK8326/
3
Moradali MF, Ghods S, Rehm BH. Pseudomonas aeruginosa Lifestyle: A Paradigm for Adaptation, Survival, and Persistence. Front Cell Infect Microbiol. 2017 Feb 15;7:39. doi: 10.3389/fcimb.2017.00039.
4
Pang Z, Raudonis R, Glick BR, Lin TJ, Cheng Z. Antibiotic resistance in Pseudomonas aeruginosa: mechanisms and alternative therapeutic strategies. Biotechnol Adv. 2019 Jan-Feb;37(1):177-192. doi: 10.1016/j.biotechadv.2018.11.013.
5
Kunz Coyne AJ, El Ghali A, Holger D, Rebold N, Rybak MJ. Therapeutic Strategies for Emerging Multidrug-Resistant Pseudomonas aeruginosa. Infect Dis Ther. 2022 Apr;11(2):661-682. doi: 10.1007/s40121-022-00591-2.
6
Thi MTT, Wibowo D, Rehm BHA. Pseudomonas aeruginosa Biofilms. Int J Mol Sci. 2020 Nov 17;21(22):8671. doi: 10.3390/ijms21228671.
7
Tuon FF, Dantas LR, Suss PH, Tasca Ribeiro VS. Pathogenesis of the Pseudomonas aeruginosaBiofilm: A Review. Pathogens. 2022 Feb 27;11(3):300. doi: 10.3390/pathogens11030300.
8
Malhotra S, Hayes D Jr, Wozniak DJ. Cystic Fibrosis and Pseudomonas aeruginosa: the Host-Microbe Interface. Clin Microbiol Rev. 2019 May 29;32(3):e00138-18. doi: 10.1128/CMR.00138-18.
9
Bhagirath, A.Y., Li, Y., Somayajula, D. et al. Cystic fibrosis lung environment and Pseudomonas aeruginosa infection. BMC Pulm Med 16, 174 (2016). doi: 10.1186/s12890-016-0339-5

Pseudomonas

References

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